CAS 1336-21-6 · REACH · European Union

Ammonium hydroxide (ammonia solution) under REACH

NH4OH (NH3 + H2O) · 氢氧化铵 / 氨水

Status: Registered. Ammonium hydroxide is fully registered under REACH. **Distinguishing pattern: Aqueous solution of anhydrous ammonia batch 38 (anhydrous ammonia at CAS 7664-41-7 separately registered); typical commercial concentrations 25 to 30% NH3 (industrial) and 5 to 10% NH3 (household cleaner) + closes ammonia chain alongside anhydrous NH3 batch 38 plus AN batch 41 plus urea batch 5 (anhydrous NH3 + H2O ⇌ NH4OH ⇌ NH4+ + OH-) + cleaning products (household + industrial degreasers) plus electronics (semiconductor wet-cleaning + photoresist developer) plus pharmaceutical buffer plus water-treatment plus fertilizer plus pulp-mill Kraft chemistry plus food-grade E527 (acidity regulator) downstream chains + moderate hazard profile (Skin Corr. 1B + Eye Dam. 1 + STOT SE 3 + Aquatic Acute 1 at concentrated ≥10% NH3 grade per harmonised CLP entry; verify exact harmonised classification per concentration band against ECHA Annex VI to CLP Table 3.1 before relying).** NOT SVHC. NOT Annex XIV. NO active EU AD case on Chinese-origin ammonium hydroxide currently (verify against EUR-Lex https://eur-lex.europa.eu/ before invoicing).

Ammonium hydroxide is fully REACH-registered with **moderate hazard profile** (Skin Corr. 1B + Eye Dam. 1 + STOT SE 3 + Aquatic Acute 1 at ≥10% NH3). NOT SVHC, NOT Annex XIV. NO active EU AD. **Closes ammonia chain alongside anhydrous NH3 batch 38 + AN batch 41 + urea batch 5**. Cleaning products + electronics + pharma + water-treatment + fertilizer + food-grade E527 downstream chains.

Listing and threshold

Substance Ammonium hydroxide (ammonia solution) (CAS 1336-21-6), NH4OH (NH3 + H2O)
Regime EU Regulation (EC) No 1907/2006: Registration, Evaluation, Authorisation and Restriction of Chemicals
Jurisdiction European Union (EU-27 plus EEA: Iceland, Liechtenstein, Norway)
Status Registered
Tonnage threshold Registration required for any importer or manufacturer placing >1 t/year on the EU market

Classifications under this regime

  • Skin Corr. 1B (causes severe skin burns and eye damage): H314 per harmonised CLP at ≥10% NH3 (verify against ECHA Annex VI to CLP Table 3.1 before relying)
  • Eye Dam. 1: H318
  • STOT SE 3: H335 (respiratory irritation)
  • Aquatic Acute 1: H400
  • GHS pictograms: GHS05 (corrosion), GHS07 (exclamation), GHS09 (environment) at ≥10% NH3
  • IARC: Not classified
  • NOT subject to Drug Precursors or Explosives Precursors scheduling
  • ADR / RID: UN 2672 Class 8 PG III at 10-35% NH3 solution; UN 2073 Class 2.2 ammonia solution >35% NH3 (verify exact UN-number per concentration against ADR before relying)
  • **Food-grade E527 acidity regulator** (verify against EU Regulation (EC) No 1333/2008 food additive Annex II at https://eur-lex.europa.eu/ for current scope)
  • **EU Pharmacopoeia monograph** for pharma-grade ammonia solution (verify monograph reference against EDQM / Ph. Eur. before relying)

Restrictions and conditions of use

  • NOT on REACH Annex XIV (verify against ECHA https://echa.europa.eu/authorisation-list)
  • NOT classified as SVHC (verify against ECHA https://echa.europa.eu/candidate-list-table)
  • NOT subject to any Annex XVII restriction
  • NO active EU AD case on Chinese-origin ammonium hydroxide currently (verify against EUR-Lex https://eur-lex.europa.eu/ before invoicing)
  • NOT in CBAM Phase 1 scope

Importer obligations

A non-EU producer cannot register directly under REACH. The EU importer of record must hold a registration or rely on an Only Representative (OR). Major Chinese ammonia / ammonium hydroxide producers (typically integrated with Haber-Bosch ammonia synthesis): Sinopec + CNPC ammonia plants, Yara China, Jiangsu Linggu Chemical, Henan Xinlianxin Fertilizer, Hubei Yihua; verify each producer-site pair against the producer's public website before relying.

Required documents

  • REACH registration number on EU side
  • SDS (Skin Corr. 1B + Eye Dam. 1 + STOT SE 3 + Aquatic Acute 1 at ≥10% NH3)
  • Customs entry HS code 282814 (ammonium hydroxide / ammonia in aqueous solution)
  • ADR documentation for UN 2672 Class 8 PG III (10-35%) or UN 2073 Class 2.2 (>35%)
  • Food / pharma grade certifications where applicable (E527 / Ph. Eur.)

Common compliance traps

The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.

  • **Aqueous solution of anhydrous NH3 batch 38; typical commercial 25-30% (industrial) + 5-10% (household)**
  • **Closes ammonia chain alongside NH3 batch 38 + AN batch 41 + urea batch 5**
  • Skin Corr. 1B + Eye Dam. 1 + STOT SE 3 + Aquatic Acute 1 at ≥10% NH3
  • NOT SVHC, NOT Annex XIV, NO active EU AD
  • **Cleaning products + electronics (semiconductor wet-cleaning + photoresist developer) + pharma buffer + water-treatment + fertilizer + pulp-mill Kraft + food-grade E527 downstream chains**
  • Major Chinese producers (Haber-Bosch integrated): Sinopec + CNPC + Yara China + Jiangsu Linggu Chemical + Henan Xinlianxin Fertilizer + Hubei Yihua

Where to read next

For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for ammonium hydroxide (ammonia solution), see the CAS 1336-21-6 sourcing reference.

For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the ammonium hydroxide (ammonia solution) cornerstone hub covers the full sourcing chain.

For the structure and history of REACH, see the REACH glossary entry.

Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.

Read next

Cross-jurisdiction profile and sourcing references

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