CAS 110-82-7 · REACH · European Union

Cyclohexane under REACH

C6H12 · 环己烷

Status: Registered. Cyclohexane is fully registered under REACH at the highest tonnage band (>1,000,000 tonnes/year). **Distinguishing pattern: KA oil (cyclohexanone plus cyclohexanol) intermediate route to caprolactam batch 14 (nylon 6 chain, ~50 percent of demand) plus adipic acid batch 51 (nylon 6,6 chain, ~50 percent of demand) via two-stage oxidation + benzene batch 22 hydrogenation production route (~95 percent globally) + Flam. Liq. 2 plus Asp. Tox. 1 plus Aquatic Chronic 1 (NEW combined).** Reg (EC) 1272/2008 harmonised: Flam. Liq. 2 (H225) plus Asp. Tox. 1 (H304) plus Skin Irrit. 2 (H315) plus STOT SE 3 (H336) plus Aquatic Acute 1 (H400) plus Aquatic Chronic 1 (H410). NOT SVHC. NOT Annex XIV. NO active EU AD case on Chinese-origin cyclohexane currently (verify against EUR-Lex https://eur-lex.europa.eu/ before invoicing).

Cyclohexane is fully REACH-registered with **moderate hazard profile**: Flam. Liq. 2 plus Asp. Tox. 1 plus Aquatic Chronic 1. NOT SVHC, NOT Annex XIV, NO active EU AD case. **KA oil intermediate route to caprolactam batch 14 plus adipic acid batch 51 chains** dominates (~50 percent each). Production: benzene batch 22 hydrogenation (~95 percent globally). Major Chinese producers: Sinopec multi-site, CNPC, Hengli Petrochemical Dalian, Wanhua Chemical Yantai.

Listing and threshold

Substance Cyclohexane (CAS 110-82-7), C6H12
Regime EU Regulation (EC) No 1907/2006: Registration, Evaluation, Authorisation and Restriction of Chemicals
Jurisdiction European Union (EU-27 plus EEA: Iceland, Liechtenstein, Norway)
Status Registered
Tonnage threshold Registration required for any importer or manufacturer placing >1 t/year on the EU market

Classifications under this regime

  • Harmonised CLP classification: Flam. Liq. 2 (H225), Asp. Tox. 1 (H304), Skin Irrit. 2 (H315), STOT SE 3 (H336), Aquatic Acute 1 (H400), Aquatic Chronic 1 (H410)
  • Signal word: DANGER. GHS pictograms: GHS02, GHS07, GHS08, GHS09
  • IARC: Group 3 (not classifiable; verify against https://monographs.iarc.who.int/list-of-classifications)
  • NOT subject to Drug Precursors or Explosives Precursors scheduling
  • ADR / RID transport classification: Class 3 (flammable liquid), UN 1145 (cyclohexane), Packing Group II

Restrictions and conditions of use

  • NOT on REACH Annex XIV (verify against ECHA https://echa.europa.eu/authorisation-list)
  • NOT classified as SVHC (verify against ECHA https://echa.europa.eu/candidate-list-table)
  • NOT subject to any Annex XVII restriction
  • NO active EU AD case on Chinese-origin cyclohexane currently
  • NOT in CBAM Phase 1 scope
  • Aquatic Chronic 1 drives wastewater-discharge compliance for downstream caprolactam batch 14 plus adipic acid batch 51 plants

Importer obligations

A non-EU producer cannot register directly under REACH. The EU importer of record must hold a registration or rely on an Only Representative (OR). Cyclohexane is structurally captive within integrated KA-oil-to-caprolactam plus KA-oil-to-adipic-acid plants in most cases. Major Chinese producers: Sinopec multi-site (Yangzi, Shanghai, Maoming, Yueyang), CNPC, Hengli Petrochemical Dalian, Wanhua Chemical Yantai (verify each producer-site pair against the producer's public website before relying).

Required documents

  • REACH registration number on EU side
  • SDS reflecting H225 / H304 / H315 / H336 / H400 / H410 classification
  • CLP labelling with GHS02 plus GHS07 plus GHS08 plus GHS09 plus DANGER
  • Customs entry HS code 290211 (cyclohexane)
  • ADR consignment note Class 3 UN 1145 PG II

Common compliance traps

The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.

  • **KA oil intermediate** to caprolactam batch 14 plus adipic acid batch 51 chains (~50 percent each)
  • Asp. Tox. 1 (aspiration hazard) drives ingestion-risk warning
  • Aquatic Chronic 1 wastewater-discharge concern
  • NOT SVHC, NOT Annex XIV, NO active EU AD
  • Major Chinese producers: Sinopec multi-site, CNPC, Hengli Petrochemical Dalian, Wanhua Chemical Yantai; China dominates global cyclohexane capacity (verify percent-of-global share against ICIS or S&P Commodity Insights before quoting)
  • Production: benzene batch 22 hydrogenation (~95 percent globally; Pt/Pd-catalyst)

Where to read next

For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for cyclohexane, see the CAS 110-82-7 sourcing reference.

For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the cyclohexane cornerstone hub covers the full sourcing chain.

For the structure and history of REACH, see the REACH glossary entry.

Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.

Read next

Cross-jurisdiction profile and sourcing references

Referenced in

5 pages across the Sourzi moat

This term shows up in 4 regulatory pages, 1 topic clusters. Sample backlinks per content type below.

Regulatory (4)

Plus 1 more regulatory pages.

Topic cluster (1)

Free download

Free PDF: the same MSDS verification template the Sourzi team uses to cross-reference factory documents against TSCA, REACH, AICIS, and CDR before booking.