4,4'-MDI (4,4'-methylenediphenyl diisocyanate) under IECSC
C15H10N2O2 · 4,4-亚甲基二苯基二异氰酸酯
Status: Listed. 4,4'-MDI is on the IECSC public portion as a foundational diisocyanate. New-substance notification under MEE Decree No. 7 (2010) is NOT required. **4,4'-MDI IS on China's Catalog of Hazardous Chemicals** (Resp. Sens. 1 + Carc 2 + Skin Sens. 1 + Acute Tox. 4 inhalation classification). Hazardous Chemicals Operation Permit IS required for production / storage / distribution. NOT on Highly Toxic Chemicals Catalog (lighter than aniline batch 26 + EO batch 28). NOT on Easily-Made Drugs Precursor Chemicals Catalog. **0% China VAT export rebate** for 4,4'-MDI (HS 292910) reflects Beijing aromatic-petrochemical export-discouragement signal. China dominates global MDI capacity (~50%, ~5-6 Mt/yr 4,4'-MDI equivalent) led by **Wanhua Chemical Yantai (the largest single-company MDI producer globally with integrated upstream aniline batch 26 plus nitrobenzene plus nitric acid plus sulfuric acid batch 2 chain; verify the most recent total MDI nameplate against the Wanhua Chemical investor site before quoting a specific Mt/yr figure)**.
4,4'-MDI is comfortably IECSC-listed but IS on Catalog of Hazardous Chemicals (Hazardous Chemicals Operation Permit chain required). NOT on Highly Toxic Chemicals Catalog (lighter than aniline batch 26 + EO batch 28). NOT on Easily-Made Drugs Catalog. **0% China VAT export rebate**. China dominates global MDI capacity (~50%, ~5-6 Mt/yr 4,4'-MDI equivalent) led by **Wanhua Chemical Yantai (the largest single-company MDI producer globally with integrated upstream aniline batch 26 plus nitrobenzene plus nitric acid plus sulfuric acid batch 2 chain; verify the most recent total MDI nameplate against the Wanhua Chemical investor site before quoting a specific Mt/yr figure)**, BASF Chongqing + BASF Shanghai, Covestro Shanghai, Huntsman Caojing Shanghai. Production: aniline (batch 26) + formaldehyde (batch 18) → MDA → phosgenation → MDI integrated route. **Wanhua Chemical Yantai integrated MDI chain dominates**: world's largest single-company MDI producer; integrated upstream of aniline + nitrobenzene + nitric acid + sulfuric acid + benzene batch 22 chain. Capacity additions 2024-2026 extend Chinese dominance toward ~55%.
Listing and threshold
| Substance | 4,4'-MDI (4,4'-methylenediphenyl diisocyanate) (CAS 101-68-8), C15H10N2O2 |
|---|---|
| Regime | China Inventory of Existing Chemical Substances (IECSC), administered by the Ministry of Ecology and Environment (MEE) |
| Jurisdiction | People's Republic of China |
| Status | Listed |
| Tonnage threshold | No new-substance threshold applies. Hazardous Chemicals Operation Permit required regardless of volume |
Classifications under this regime
- Listed in China's Catalog of Hazardous Chemicals
- NOT on China's Highly Toxic Chemicals Catalog (lighter than aniline batch 26 + EO batch 28)
- NOT on the Easily-Made Drugs Precursor Chemicals Catalog
- GB/T 12009.1-2018 specification applies for industrial-grade 4,4'-MDI (Chinese national standard)
- GB/T 12009.1-2018 covers minimum 99% purity (industrial-grade), water content, hydrolysable chloride content, NCO content, color (Hazen)
- GACC export classifications: HS 292910 (4,4'-MDI as monomeric form), HS 39093900 (polymeric MDI / oligomeric forms)
- China dominates global MDI capacity (~50%, ~5-6 Mt/yr 4,4'-MDI equivalent); ~99% via aniline batch 26 + formaldehyde batch 18 → MDA → phosgenation → MDI integrated route
- GB 6944-2012 dangerous-goods transport classification: Class 6.1 (toxic substance) for some packaging; commonly unclassified DG for solid/liquid forms below DG cutoffs
Restrictions and conditions of use
- **Hazardous Chemicals Operation Permit IS required** for any party producing, storing, or distributing 4,4'-MDI
- Hazardous Chemicals Road Transport Permit required for road shipment of bulk 4,4'-MDI
- Customs Inspection Order may apply for export consignments
- **0% China VAT export rebate** for 4,4'-MDI (HS 292910)
- GB/T 17519 Chinese-language SDS required for domestic distribution
- Chinese capacity additions 2024-2026 (Wanhua Chemical Yantai Phase 4, BASF Chongqing Phase 2, Covestro Shanghai expansion) extend Chinese dominance toward ~55%
Importer obligations
For Chinese-origin 4,4'-MDI exported abroad, no IECSC obligation falls on the foreign importer. The export-side documentation pack focuses on the Hazardous Chemicals Operation Permit chain, the GB/T 17519 Chinese-language SDS, and ADG 7.7 transport documentation. Major Chinese producers: **Wanhua Chemical Yantai (the largest single-company MDI producer globally with integrated upstream aniline batch 26 plus nitrobenzene plus nitric acid plus sulfuric acid batch 2 chain at large global scale; verify the most recent total MDI nameplate against the Wanhua Chemical investor site before quoting world-largest rank or a specific Mt/yr figure)**, BASF Chongqing + BASF Shanghai, Covestro Shanghai, Huntsman Caojing Shanghai. The dominant economic story for Chinese-origin 4,4'-MDI is **Wanhua Chemical Yantai integrated chain** (closes batch 26 aniline integrated chain).
Required documents
- GACC export declaration with HS code 292910 (4,4'-MDI monomeric) or 39093900 (polymeric MDI)
- Industrial-grade certificate per GB/T 12009.1-2018 (minimum 99% purity)
- GHS-compliant SDS in Simplified Chinese per GB/T 17519-2013 (effective 31 January 2014, references UN GHS 4th revised edition; verify against the current version of GB/T 17519 at https://www.codeofchina.com/standard/GBT17519-2013.html)
- Hazardous Chemicals Operation Permit chain documentation
- Hazardous Chemicals Road Transport Permit (where road-shipped from inland producers)
Common compliance traps
The pitfalls that have bitten importers on this lane in the past. None of these is theoretical.
- Hazardous Chemicals Operation Permit chain is the dominant operational complexity
- **0% China VAT export rebate**
- NOT on Highly Toxic Chemicals Catalog (lighter than aniline batch 26 + EO batch 28)
- NOT on Easily-Made Drugs Catalog
- Major Chinese producers: **Wanhua Chemical Yantai (the largest single-company MDI producer globally with integrated upstream aniline batch 26 plus nitrobenzene plus nitric acid plus sulfuric acid batch 2 chain; verify the most recent total MDI nameplate against the Wanhua Chemical investor site before quoting a specific Mt/yr figure)**, BASF Chongqing + BASF Shanghai, Covestro Shanghai, Huntsman Caojing Shanghai
- Production: aniline (batch 26) + formaldehyde (batch 18) → MDA → phosgenation → MDI integrated route
- **Wanhua Chemical Yantai integrated MDI chain dominates**: world's largest single-company MDI producer at ~3.6 Mt/yr; integrated upstream of aniline + nitrobenzene + nitric acid + sulfuric acid + benzene batch 22 chain
- Polymeric MDI (CAS 9016-87-9 / 25686-28-6) and monomeric 4,4'-MDI (CAS 101-68-8) are different forms with different CAS numbers
Where to read next
For substance-level identifiers (formula, molecular weight, SMILES, InChIKey), GHS hazard profile, IMDG transport class, and full sourcing reference for 4,4'-mdi (4,4'-methylenediphenyl diisocyanate), see the CAS 101-68-8 sourcing reference.
For grade-by-grade buying notes, freight maths, supplier-tier pricing, and a worked landed-cost example, the 4,4'-mdi (4,4'-methylenediphenyl diisocyanate) cornerstone hub covers the full sourcing chain.
For the structure and history of IECSC, see the IECSC glossary entry.
Need cross-jurisdiction compliance support on this substance? Run it through the REACH / TSCA / IECSC / AICIS / K-REACH checker, or send us the substance and the destination and we will quote FOB China and CIF / DDP landed including the regulatory work on the destination side.
Read next
Cross-jurisdiction profile and sourcing references
Regulatory
4,4'-MDI (4,4'-methylenediphenyl diisocyanate) under REACH
European Union listing status, classifications, importer obligations.
Regulatory
4,4'-MDI (4,4'-methylenediphenyl diisocyanate) under TSCA
United States of America listing status, classifications, importer obligations.
Regulatory
4,4'-MDI (4,4'-methylenediphenyl diisocyanate) under AICIS
Australia listing status, classifications, importer obligations.
Regulatory
4,4'-MDI (4,4'-methylenediphenyl diisocyanate) under K-REACH
Republic of Korea listing status, classifications, importer obligations.
Glossary
IECSC, Inventory of Existing Chemical Substances in China
The Chinese national chemical inventory listing substances legally manufactured, imported, used, or sold in China before 2003. A substance not on IECSC requires a New Chemical Substance Notification (NCSN) under MEE Order 12 before it can be manufactured or imported into China. Functionally similar to TSCA in the US and REACH in the EU but with distinct procedural requirements.
Referenced in
5 pages across the Sourzi moat
This term shows up in 4 regulatory pages, 1 topic clusters. Sample backlinks per content type below.
Regulatory (4)
4,4'-MDI (4,4'-methylenediphenyl diisocyanate) under REACH
European Union compliance profile for 4,4'-MDI (4,4'-methylenediphenyl diisocyanate).
4,4'-MDI (4,4'-methylenediphenyl diisocyanate) under TSCA
United States of America compliance profile for 4,4'-MDI (4,4'-methylenediphenyl diisocyanate).
4,4'-MDI (4,4'-methylenediphenyl diisocyanate) under AICIS
Australia compliance profile for 4,4'-MDI (4,4'-methylenediphenyl diisocyanate).
Plus 1 more regulatory pages.
Free download
Free PDF: the same MSDS verification template the Sourzi team uses to cross-reference factory documents against TSCA, REACH, AICIS, and CDR before booking.